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National trial safely scaled back prescribing of a powerful antipsychotic for...

Warning letters can safely cut prescribing of a powerful but risky antipsychotic, according to a new study. Researchers used Medicare data to study the effects of the letters on hundreds of thousands...

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Imaging technique shows new details of peptide structures

Researchers outline how they used a chemical probe to light up interlocking peptides. Their technique will help scientists differentiate synthetic peptides from toxic types found in Alzheimer's disease.

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New group training tool for the prevention of dementia

The system is already in use in retirement homes. Researchers have now tested how effective it is in a scientific study.

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The vicious cycle of protein clumping in Alzheimer's disease and normal aging

To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins....

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Climbing the social ladder may slow dementia

Researchers analyzed data from the Japan Gerontological Evaluation Study and found that socioeconomic status (SES) transitions affect dementia risk. Specifically, upward SES mobility is greater...

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Naturally occurring substance in pomegranates can improve treatment of...

A substance naturally occurring in i.a. pomegranates, strawberries and walnuts can improve memory and treatment of Alzheimer's disease, a new study concludes.

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What factors predict when older adults will stop driving?

What factors lead older adults to stop driving? A new study followed older adults who had no memory or thinking problems to examine this question.

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Subtle cognitive decline precedes end to driving for older adults

Even slight cognitive changes can affect an older person's decision to stop driving, according to a new study. The findings suggest that routine cognitive testing -- in particular, the kind of...

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Altering cellular interactions around amyloid plaques may offer novel...

Researchers made a significant breakthrough in Alzheimer's disease research by identifying a novel way to potentially slow down or even halt disease progression. The study, which focuses on the role of...

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First hints of memory problems associated with changes in the brain

People who report early memory problems and whose partners also suspect they have memory problems have higher levels of tau tangles in the brain, a biomarker associated with Alzheimer's disease.

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Study examines prescribing patterns of drug associated with cognitive impairment

A new study is one of the first explorations of prescribing patterns of tricyclic antidepressants for treatment of diabetic peripheral neuropathy at healthcare facilities predominantly serving diverse...

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Astrocytes induce sex-specific effects on memory

Scientists have uncovered the first evidence that astrocyte receptors can trigger opposite effects on cognitive function in male and female preclinical models. The findings point to astrocytes, brain...

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How stress knocks out your cognitive reserve

While mentally stimulating activities and life experiences can improve cognition in memory clinic patients, stress undermines this beneficial relationship.

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Vigorous exercise may preserve cognition in high-risk patients with hypertension

People with high blood pressure have a higher risk of cognitive impairment, including dementia, but a new study suggests that engaging in vigorous physical activity more than once a week can lower that...

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First-of-its-kind test can predict dementia up to nine years before diagnosis

Researchers have developed a new method for predicting dementia with over 80% accuracy and up to nine years before a diagnosis. The new method provides a more accurate way to predict dementia than...

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Detecting early linguistic signs of dementia by studying the natural speech...

A study led by linguists has found that early linguistic signs of dementia can be detected through the study of the natural speech of senior Singaporeans. The novel study revealed that participants...

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Depressive symptoms may hasten memory decline in older people

The researchers concluded that depression and memory were closely interrelated, with both seeming to affect each other.

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Preparing for a world where Alzheimer's disease is treatable

Drugs with the potential to change the course of Alzheimer's disease are expected to be approved by mid-year in the UK. Healthcare services may need to change to ensure that all patients have equitable...

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Maternal inheritance of Alzheimer's disease tied to increased risk of...

Researchers analyzed 4,400 cognitively unimpaired adults with amyloid imaging, finding increased amyloid in those who reported that their mothers had symptoms of Alzheimer's disease (AD). Increased...

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Sound stimulation with precise timings can help understand brain wave functions

Using sound to stimulate certain brain waves has the potential to help those with dementia or cognitive decline sleep better, reveals a new study. Sleep disturbances are a common feature in dementia...

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